Faculty of Science
Microbiology and Immunology

Yossef Av-Gay

Professor

Yossef Av-Gay

Our primary research focus is Tuberculosis (TB) pathogenesis. TB is caused by Mycobacterium tuberculosis (Mtb), which is one of the most devastating infectious agents in the world today.  One-third of the world’s population is exposed to TB, which kills nearly two million people annually with over 10 million new infections taking place each year. Synergy with the human immunodeficiency virus (commonly known as HIV), along with the emergence of multidrug resistant strains of Mtb has reaffirmed TB as a tremendous public health threat worldwide today.

Our research interest activities cover multiple aspects of Mtb physiology and pathogenesis and have now expanded into three main research areas:  (i) Signal transduction in mycobacteria and between Mtb and the host macrophage, (ii)  Novel approaches for drug discovery focusing on the intracellular lifestyle of Mtb and (iii) post translational modifications, phosphorylation and thiol modifications, and their role in TB pathogenesis.

View Publications

  • Antimicrobial Discovery and Resistance
  • Microbial Physiology and Pathogenesis

Yossef Av-Gay

Professor

Department of Microbiology and Immunology
Faculty of Medicine, Division of Infectious Diseases

yossi@mail.ubc.ca

Office Tel: 604-822-3432

Office Location: 2503 - 2350 Health Sciences Mall, Life Sciences Centre

Lab Tel: 604-822-6027

Lab Location: 2540 - 2350 Health Sciences Mall, Life Sciences Centre

Musqueam First Nation land acknowledegement

We honour xwməθkwəy̓ əm (Musqueam) on whose ancestral, unceded territory UBC Vancouver is situated. UBC Science is committed to building meaningful relationships with Indigenous peoples so we can advance Reconciliation and ensure traditional ways of knowing enrich our teaching and research.

Learn more: Musqueam First Nation

Microbiology and Immunology

1365–2350 Health Sciences Mall
Vancouver, BC Canada
V6T 1Z3

Faculty of Science

Office of the Dean, Earth Sciences Building
2178–2207 Main Mall
Vancouver, BC Canada
V6T 1Z4
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