Faculty of Science
Microbiology and Immunology

Characterization of acetovanillone degradation in wild-type and engineered Rhodococcus aromaticivorans RHA1

A gene schematic and a chemical reaction

Publication Date

Publication Journal

Applied and Environmental Microbiology

Author(s)

Anne T. Lalande, Megan E. Wolf, Logan D. Robeck, and Lindsay D. Eltis

Aromatic compounds derived from lignin, an abundant component of plant biomass, have tremendous potential as a sustainable replacement for petroleum in the manufacture of valuable chemicals. In this paper, the authors characterized a pathway that degrades an important class of lignin-derived aromatic compounds. Using the organism Rhodococcus aromaticivoransRHA1, they compared the efficiency of several pathways and identified key bottlenecks and competing activities, thereby laying the groundwork for engineering lignin-transforming microbial cell factories.

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Microbiology and Immunology

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