Seminar - Dr. Aaron Reinke
Dr. Aaron Reinke
MBIM Seminar Series
Starts
Oct 08, 2024 - 12:30 pmAdd to Calendar 2024-10-08 19:30:00 2024-10-08 19:30:00 Seminar - Dr. Aaron Reinke

Seminar: Protection against microsporidia infection by intergenerational immunity and the microbiome

 

Abstract: Microsporidia are fungal-related, obligate intracellular parasites that can infect most types of animals including humans. Nematocida parisii is a microsporidian pathogen that commonly infects the model organism C. elegans in the wild. Using this system we have identified and characterized a robust immune response that C. elegans parents transfer to their offspring. We have also examined how bacteria can impact microsporidia infection. Our findings suggest that interactions between members of the C. elegans microbiome and N. parisii are common and that these bacteria influence microsporidia growth by modulating host metabolism and by producing compounds that limit microsporidia infection.

LSC 3 (Life Sciences Institute - 2350 Health Sciences Mall) MBIM itsupport@microbiology.ubc.ca America/Vancouver public
Ends
Oct 08, 2024 - 1:30 pm
Location
LSC 3 (Life Sciences Institute - 2350 Health Sciences Mall)
Hosted by
Dr. Kayla King
Presenter title
Associate professor in Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
Presenter name
Dr. Aaron Reinke

Seminar: Protection against microsporidia infection by intergenerational immunity and the microbiome

 

Abstract: Microsporidia are fungal-related, obligate intracellular parasites that can infect most types of animals including humans. Nematocida parisii is a microsporidian pathogen that commonly infects the model organism C. elegans in the wild. Using this system we have identified and characterized a robust immune response that C. elegans parents transfer to their offspring. We have also examined how bacteria can impact microsporidia infection. Our findings suggest that interactions between members of the C. elegans microbiome and N. parisii are common and that these bacteria influence microsporidia growth by modulating host metabolism and by producing compounds that limit microsporidia infection.